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The following links give access to product information, scientific publications and educational graphics that give a detailed explanation of Starpharma's dendrimer nanotechnology. (Note: All files below will open in a new window)

Product Information:

VivaGel™
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ADME Engineering™
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Angiogenesis Inhibition
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Dendrimer Overview
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Macromolecule Surface Functionalisation
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Scientific Publications:

Coming soon
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Animations / Graphics:

	Dendrimer modified for pharmaceutical activity: red and blue groups are active; yellow groups modify bioavailability and other pharmacokinetic properties; and green groups target specific organs and tissues. Click here to view image Click here to view animation
	A dendrimer is capable of polyvalent interactions with biological targets, such as receptors on a cell membrane. Click here to view image Click here to view animation
	Typical small molecule drugs interact with single biological targets or receptors. Click here to view image
	Dendrimers are synthesised in a series of generations and are similar in size to naturally occurring biological proteins. Click here to view image
	Dendrimers are larger than typical drug molecules such as aspirin, shown here. Click here to view image
	A red blood cell, ~7,000 nm. Click here to view image
	A bacterium, ~1,000 nm. Click here to view image
	A virus, ~100 nm. Click here to view image
	Aspirin, ~1 nm. Click here to view image
	Size comparison of various biological structures and a 5 nm dendrimer. A hair is ~50,000 nm in diameter and is shown behind representations of a red blood cell, a bacterium and the HIV virus. Click here to view image
	How does VivaGel™ work? View an animation about Starpharma's microbicide that is being developed for prevention of HIV and other sexually transmitted infections. Click here to view image Click here to view animation
	The HIV virus (yellow and purple) infects human T-cells (pink) by attaching to receptors on the surface of the T-cell. Click here to view image
	SPL7013, the active dendrimer ingredient of Starpharma's topical microbicide, VivaGel™ , binds to surface proteins on HIV, preventing the virus from infecting human T-cells. Click here to view image
	Several dendrimers may be assembled into larger, defined structures such as layers, spheres and chains. Click here to view image
	Dendrimers may be used to transform white light into single wavelength light. Click here to view image